Case Control Study
Copyright ©The Author(s) 2016.
World J Gastrointest Oncol. Jun 15, 2016; 8(6): 520-525
Published online Jun 15, 2016. doi: 10.4251/wjgo.v8.i6.520
Table 2 Genotype and allele frequencies of the interleukin 1β -511 C/T and +3954 C/T polymorphisms in pancreatic adenocarcinoma, pancreatic neuroendocrine tumor and intraductal papillary mucinous neoplasm patients and controls
Controls (n = 98)PDAC (n = 85)P; OR (95%CI)pNET (n = 51)P; OR (95%CI)IPMN (n = 19)P; OR (95%CI)
-511 C/T
CC4435113161
CT47440.64; 1.18 (0.64-2.16)310.04; 2.23 (1.04-4.81)100.59; 1.56 (0.52-4.65)
TT761; 1.08 (0.33-3.49)70.04; 3.95 (1.13-13.84)30.16; 3.14 (0.64-15.56)
CT + TT54500.37; 1.36 (0.75-2.44)380.02; 2.38 (1.13-5.02)130.32; 1.76 (0.62-5.03)
C allele1351141571221
T allele61560.74; 1.09 (0.7-1.69)450.03; 1.75 (1.07-2.86)160.19; 1.61 (0.79-3.28)
+3954 C/T
CC4550133181
CT44280.08; 0.57 (0.31-1.07)160.07; 0.49 (0.24-1.03)100.79; 1.28 (0.46-3.54)
TT970.59; 0.7 (0.24-2.04)20.19; 0.3 (0.06-1.49)11; 0.62 (0.07-5.64)
CT + TT53350.1; 0.59 (0.33-1.07)180.04; 0.46 (0.23-0.93)110.81; 1.18 (0.43-3.15)
C allele1341281821261
T allele62420.16; 0.71 (0.45-1.12)200.03; 0.53 (0.29-0.94)120.85; 1.07 (0.51-2.25)