Copyright
©The Author(s) 2016.
World J Gastrointest Oncol. May 15, 2016; 8(5): 450-458
Published online May 15, 2016. doi: 10.4251/wjgo.v8.i5.450
Published online May 15, 2016. doi: 10.4251/wjgo.v8.i5.450
Burdens and harms | Benefits | |||||||||||
CISNETmodel | Test | Stool tests | Total COL | Complications | LYG | CRC DA | CRC incidence reduction | CRC mortality reduction | % of COL 10y LYG | COL per LYG | Complications per LYG | Complications per DA |
SimCRC | COL 10y | 0 | 4007 | 14 | 275 | 24 | 81% | 87% | 100% | 15 | 0.051 | 0.58 |
FIT3y | 6887 | 971 | 6 | 212 | 18 | 45% | 65% | 77% | 5 | 0.028 | 0.33 | |
hsFOBT3y | 6456 | 1286 | 7 | 212 | 18 | 47% | 66% | 77% | 6 | 0.033 | 0.39 | |
mt-sDNA3y | 5990 | 1701 | 9 | 250 | 22 | 63% | 78% | 91% | 7 | 0.036 | 0.41 | |
MISCAN | COL 10y | 0 | 4101 | 15 | 248 | 22 | 62% | 79% | 100% | 17 | 0.060 | 0.68 |
FIT3y | 6795 | 995 | 7 | 176 | 15 | 28% | 55% | 71% | 6 | 0.040 | 0.47 | |
hsFOBT3y | 6302 | 1296 | 8 | 175 | 15 | 30% | 55% | 71% | 7 | 0.046 | 0.53 | |
mt-sDNA3y | 5779 | 1714 | 9 | 215 | 19 | 43% | 68% | 87% | 8 | 0.042 | 0.49 | |
CRC-SPIN | COL 10y | 0 | 4049 | 15 | 270 | 24 | 88% | 90% | 100% | 15 | 0.056 | 0.62 |
FIT3y | 6857 | 1081 | 7 | 178 | 16 | 49% | 59% | 66% | 6 | 0.039 | 0.44 | |
hsFOBT3y | 6498 | 1317 | 8 | 183 | 16 | 53% | 61% | 68% | 7 | 0.044 | 0.50 | |
mt-sDNA3y | 5927 | 1827 | 10 | 226 | 20 | 68% | 76% | 84% | 8 | 0.044 | 0.50 |
- Citation: Berger BM, Levin B, Hilsden RJ. Multitarget stool DNA for colorectal cancer screening: A review and commentary on the United States Preventive Services Draft Guidelines. World J Gastrointest Oncol 2016; 8(5): 450-458
- URL: https://www.wjgnet.com/1948-5204/full/v8/i5/450.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v8.i5.450