Role of Helicobacter pylori in gastric cancer: Updates

doi:10.4251/wjgo.v8.i2.147

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2016; 8(2): 147-158
Published online Feb 15, 2016. doi: 10.4251/wjgo.v8.i2.147

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Figure 4 Representation of Helicobaceter pylori major virulence factor, vacuolating cytotoxin containing three domain 1: signal sequence(S) 2: middle region (m) 3: recently identified intermediate region (i) s, m and i region are further stratified into the subtypes s1, s2, m1, m2 and i1, i2 respectively. TLR4: Toll like receptor 4; T4SS: Type IV secretion system; VacA: Vacuolating cytotoxin; CagPAI: Cag pathogenicity island; GC: Gastric cancer; ROS: Reactive oxygen species.

Citation: Khatoon J, Rai RP, Prasad KN. Role of Helicobacter pylori in gastric cancer: Updates. World J Gastrointest Oncol 2016; 8(2): 147-158
URL: https://www.wjgnet.com/1948-5204/full/v8/i2/147.htm
DOI: https://dx.doi.org/10.4251/wjgo.v8.i2.147