Impact of RAS and BRAF mutations on carcinoembryonic antigen production and pattern of colorectal metastases

Table 2 RAS and BRAF status and primary tumor location and pattern of metastasis

			BRAF		BRAF		P	RAS		RAS		P
	All		MT		WT			MT		WT
	n	%	n	%	n	%		n	%	n	%
Primary lesion	Rectal	43	25	0	--	43	100	0.022	23	53	20	47	0.23
	Left colon	79	45	5	6	74	94		34	43	45	57
	Right colon	52	30	6	12	46	88		30	58	22	42
Site of metastasis	Lung	72	42	3	4	69	96	0.36	41	57	31	42	0.17
	Liver	98	56	5	5	93	95	0.54	46	47	52	53	0.44
	Peritoneal	49	28	5	10	44	90	0.3	23	47	26	53	0.74

n: Number of patients; MT: Mutant; WT: Wild type.