Inflammation-based factors and prognosis in patients with colorectal cancer

Table 1 Previously reported correlations between various inflammation-based factors and the prognosis

Inflammation-based factors	Ref.	Year	Timing of measurement	n	TNM staging	Treatment	Survival analysis	Summary results
CRP	Nozoe et al[19]	1998	Preoperation	120	I-IV	Resection	OS	Positive
	Toiyama et al[20]	2013	Preoperation	84	I-III	Resection and CRT	DFS, OS	Positive
	Shibutani et al[21]	2014	Preoperation	144	IV	Resection and CT	PFS, OS	Positive
GPS	Sugimoto et al[22]	2012	Preoperation	166	II	Resection	OS	Positive
	Kishiki et al[23]	2013	Pretreatment	79	IV	CT	OS	Positive
	Ishizuka et al[24]	2013	Preoperation	108	IV	Resection	OS	Positive
NLR	Chua et al[26]	2011	Pre and post treatment	171	IV	CT	OS	Positive
	Chua et al[26]	2011	Preoperation	674	I-IV	Resection	OS	Positive
	Li et al[27]	2014	-	-	Meta-analysis	-	DFS, OS	Positive
OPNI	Nozoe et al[28]	2012	Preoperation	219	I-IV	Resection	OS	Positive
	Maeda et al[29]	2014	Preoperation	100	IV	Resection and CT	OS	Positive
	Ikeya et al[30]	2014	Pre and post treatment	80	IV	CT	OS	Positive
PLR, NLR	Kwon et al[31]	2012	Preoperation	200	I-III	Resection	OS	Positive
GPS, NLR	Maeda et al[32]	2013	Preoperation	94	IV	resection and CT	OS	Positive

CRP: C-reactive protein; GPS: Glasgow Prognostic Score; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; CT: Chemotherapy; CRT: Chemoradiotherapy; OS: Overall survival; DFS: Disease-free survival; PFS: Progression-free survival.