Association of endothelial nitric oxide synthase gene T-786C promoter polymorphism with gastric cancer

doi:10.4251/wjgo.v7.i7.87

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jul 15, 2015; 7(7): 87-94
Published online Jul 15, 2015. doi: 10.4251/wjgo.v7.i7.87

Table 3 Distribution of genotype frequencies in patients and control subjects with regard to addictions

Characteristic	Cases n (%)	Controls n (%)	χ²	OR (95%CI)	P value
Smoking status
T/T genotype
Smokers	2 (66.67)	4 (18.18)
Nonsmokers	1 (33.33)	18 (81.82)	1.263	9.000 (0.44-339.56)	0.133
T/C genotype
Smokers	7 (58.33)	5 (17.24)
Nonsmokers	5 (41.67)	24 (82.76)	5.080	6.720 (1.21-40.80)	0.020^a
C/C genotype
Smokers	104 (77.04)	23 (23.23)
Nonsmokers	31 (22.96)	76 (76.77)	64.475	11.086 (5.74-21.58)	0.000^b
Alcoholism
T/T genotype
Alcoholics	2 (66.67)	7 (31.82)
Non-alcoholics	1 (33.33)	15 (68.18)	0.290	4.286 (0.23-145.14)	0.530
T/C genotype
Alcoholics	10 (83.33)	9 (31.03)
Non-alcoholics	2 (16.67)	20 (68.97)	7.351	11.11 (1.68-93.07)	0.005^b
C/C genotype
Alcoholics	113 (83.70)	48 (48.48)
Non-alcoholics	22 (16.30)	51 (51.52)	31.385	5.457 (2.86-10.46)	0.000^b

^aP < 0.05,

^bP < 0.01.

Citation: Krishnaveni D, Amar Chand B, Shravan Kumar P, Uma Devi M, Ramanna M, Jyothy A, Pratibha N, Balakrishna N, Venkateshwari A. Association of endothelial nitric oxide synthase gene T-786C promoter polymorphism with gastric cancer. World J Gastrointest Oncol 2015; 7(7): 87-94
URL: https://www.wjgnet.com/1948-5204/full/v7/i7/87.htm
DOI: https://dx.doi.org/10.4251/wjgo.v7.i7.87