Polymorphisms in mucin genes in the development of gastric cancer

Table 2 Description of the studied single nucleotide polymorphisms in mucin genes

Gene	Chromosome	SNPs	Wild alleles	Mutated alleles	Contig position1	Location2
MUC1	1q21	rs4072037	A	G	12007689	T22T
		rs2070803	C	T	12000652	3’ flanking region
		rs6427184	A	G	11965720	3’ flanking region
		rs4971052	C	T	11968955	3’ flanking region
		rs4276913	A	G	11974610	3’ flanking region
		rs4971088	T	A	11985820	3’ flanking region
		rs4971092	T	C	11986883	3’ flanking region
		rs2990245	T	C	12043084	5’ flanking region
		rs9628662	T	G	12051963	5’ flanking region
		rs9426886	T	A	11994691	3’ flanking region
		rs3814316	C	T	11992655	3’ flanking region
		rs1045253	T	C	12046857	5’ flanking region
MUC5AC	11p15.5	rs1541314	G	A	1182293	3’ flanking region
		rs2014486	A	G	1177573	3’ flanking region
		rs2075859	C	T	1169258	3’ flanking region
		rs2672785	C	T	1165711	3’ flanking region
		rs2735733	C	T	1180410	3’ flanking region
		rs7118568	C	G	1162850	3’ flanking region
		rs868903	T	C	1161460	3’ flanking region
		rs4963049	A	G	1155197	3’ flanking region
		rs3793966	C	T	1221718	3’ flanking region
		rs3793964	C	T	1220752	3’ flanking region
		rs3750919	G	A	1211601	3’ flanking region
		rs5743942	C	T	1232798	3’ flanking region
		rs4963062	G	A	1245411	3’ flanking region
		rs885454	C	T	1162161	3’ flanking region
		rs6578810	T	G	1209349	3’ flanking region
		rs11040869	G	A	1203382	3’ flanking region
		rs7118481	G	C	1267108	3’ flanking region
		rs7105198	G	C	1086133	5’ flanking region
MUC6	11p15.5	rs1128413	C	T	950694	3’ flanking region
		rs4077293	C	T	936522	3’ flanking region
		rs7483870	C	T	916019	3’ flanking region
		rs7943115	G	A	913885	3’ flanking region
		rs11602663	C	T	960778	Intronic
		rs11605303	G	A	978110	5’ flanking region
		rs10902076	G	C	1006044	5’ flanking region
		rs2071174	C	T	1013712	5’ flanking region
		rs11245936	G	A	1026266	5’ flanking region
		rs10794359	C	T	991715	5’ flanking region
		rs7112267	C	T	996981	5’ flanking region
		rs12574439	G	C	997948	5’ flanking region
		rs7119740	C	G	1000419	5’ flanking region
		rs11601642	C	A	1002509	5’ flanking region
		rs4076950	C	T	955021	Intronic
		rs7481521	G	A	967811	V619M
		rs11246384	C	T	970448	Intronic
		rs6597947	G	T	977029	5’ flanking region
		rs9794921	G	T	979867	5’ flanking region
MUC2	11p15.5	rs10902073	C	A	1000934	5’ flanking region
		rs10794281	C	T	1003149	5’ flanking region
		rs2856082	C	G	1011562	5’ flanking region
		rs2071174	C	T	1013712	5’ flanking region
		rs7396030	C	T	1025368	Intronic
		rs11245936	G	A	1026366	G832S
		rs7944723	C	G	1039802	P1832P
		rs6421972	G	A	1042586	I2154T
		rs10794293	C	T	1045031	Intron
		rs11245954	A	G	1047170	V2459V
		rs7480563	G	A	1047741	T2524P
		rs7126405	G	A	1049388	Q2653P
		rs3924453	G	A	1051898	3’ flanking region
		rs4077759	C	T	1052068	3’ flanking region
		rs2856111	T	C	1015747	L58P
		rs11825977	A	G	1015920	V116M

¹Based on contig NT_004487.20 for MUC1 gene, and contig NT_009237.19 for MUC5AC, MUC6 and MUC2 genes;

²SNP location relative to each gene in the region. SNPs: Single nucleotide polymorphisms.