Primary tumor resection in colorectal cancer with unresectable synchronous metastases: A review

Table 4 Complications related to in situ tumor in patients with unresectable stage IV colorectal cancer treated with chemotherapy as initial management n (%)

Ref.	No. of patients	Primary tumor-related complications (%)	Type of complication during chemotherapy			Surgery required for complication (%)
			Obstruction	Bleeding	Perforation
Scoggins et al[82]	23	9	2 (9)	0	0	9
Sarela et al[71]	24	29	4 (17)	0	0	21
Ruo et al[44]	103	29	30 (29)	0	0	29
Tebbut et al[34]	82	23	11 (13)	3 (4%)	5 (6)	10
Michel et al[90]	23	22	5 (22)	0	0	22
Benoist et al[79]	27	15	4 (15)	0	0	15
Muratore et al[75]	35	8.5	2 (6)	1 (3%)	0	3
Galizia et al[38]	23	30	4 (17)	1 (4%)	2 (9)	17
Evans et al[70]	52	23	3 (6)	9 (17%)	0	2
Poultsides et al[76]	233	11	18 (8)	0	5 (2)	7
Karoui et al[33]	123	19	21 (17)	0	2 (2)	12
McCahill et al[77]	86	16	10 (12)	0	1 (1)	12