Modulators affecting the immune dialogue between human immune and colon cancer cells

Figure 2 Schematic presentation of the way immune modulators modify the cross-talk between peripheral blood mononuclear cells and cancer cells. Following alteration of the immune dialogue between these two cell types, the modulators inhibit cancer cell-stimulated peripheral blood mononuclear cells (PBMC) to generate pro-inflammatory cytokine (red dots), acting as cancer promoters.