Prognostic value of baseline FDG uptake on PET-CT in esophageal carcinoma

Table 4 Summary of literature reporting on prognostic value of maximum standardized uptake value in patients with esophageal carcinoma

Ref.	Patients (n)	Adeno-carcinoma (%)	Treatment intention of studied group	Median (or mean) SUVmax	SUVmax significant on univariate analysis	SUVmax significant on multivariate analysis	Other significant associations on multivariate analysis
Fukunaga et al[4], 1998	48	Not stated	Curative	7	Yes	Not assessed	Not assessed
Choi et al[5], 2004	69	0%	Curative	6.3/13.7 (thresholds)	Yes	No	UICC stage
Hong et al[6], 2005	47	87%	Curative	Not stated	No	No	Number of abnormalities on PET-CT
Stahl et al[7], 2005	40	100%	Curative	10.5	No	Not assessed
van Westreenen et al[8], 2005	40	70%	Curative and palliative	6.7	Yes	No	Treatment
Cerfolio et al[9], 2006	89	53%	Curative	6.6	Yes	Yes	UICC stage
Choi et al[10], 2006	51	0%	Curative	Not stated	Yes	No	UICC stage, N1 status (on PET-CT), immunohistochemical markers
Westerterp et al[11], 2008	26	100%	Curative	0.26	Yes	Not assessed
Omloo et al[12], 2008	125	85%	Curative	0.27	Yes	No	UICC stage
Cheze-Le Rest et al[13], 2008	47	77%	Curative	9	Yes	Yes	Treatment, number of abnormalities on PET-CT
Chatterton et al[14], 2008	129	19%	Curative and palliative	8.2	No	Not assessed	Not assessed
Makino et al[15], 2008	38	100%	Curative	11.1	Yes	No	N1 status (on PET-CT)
Javeri et al[16], 2009	161	100%	Curative	10.1	No	No
Kato et al[17], 2009	184	0%	Curative	4.5	Yes	Yes	N1 status
Rizk et al[18], 2009	189	100%	Curative	4.5 (preset threshold)	Yes	Not assessed	Not assessed
Sepesi et al[19], 2009	72	83%	Curative	6.2	Yes	Yes
Shenfine et al[20], 2009	45	100%	Curative	5.7	Yes	No	UICC stage
Hyun et al[21], 2010	151	3%	Curative and palliative	17.2	Yes	No	UICC stage, metabolic tumor volume
Brown et al[22], 2012	103	80%	Curative	6.4 (early)/8.8 (later scans)	Yes	No	N1 status, age
Gillies et al[23], 2012	121	100%	Curative	8.5	Yes	No	N1 status (on PET-CT)
Chan et al[24], 2013	185	75%	Curative and palliative	8.9	Yes	No	N1 status, tumor volume on EUS

SUV_max: Maximum standardized uptake value; UICC: Union for International Cancer Control; PET-CT: Positron emission tomography-computed tomography.