Neoadjuvant treatment for esophageal squamous cell carcinoma

Table 1 Neoadjuvant radiotherapy treatment and outcomes for esophageal squamous cell carcinoma

Ref.	Year of publication	Histology	Treatment	n	Median survival (mo)	5-yr overall survival (%)	P
Launois et al[17]	1981	SCC	RT 40 Gy → Surgery	77	10	10	NS
			Surgery	57	12	12
Gignoux et al[18]	1987	SCC	RT 33 Gy → Surgery	106	11	11	NS
			Surgery	102	11	10
Arnott et al[19]	1992	AC/SCC	RT 20 Gy → Surgery	90	8	9	NS
		(36%)	Surgery	86	8	17
Nygaard et al[20]	1992	SCC	RT 35 Gy → Surgery	48		211	0.080
			Surgery	41		9
Wang et al[21]	1989	SCC	RT 40 Gy → Surgery	104		35	NS
			Surgery	102		30
Cao et al[22]	2009	SCC	RT 40 Gy → Surgery	118		701	0.0051
			Surgery	118		53
Chu et al[23]	1994	SCC	RT 24-53 Gy → Surgery	40	11	10	NS
			Surgery → RT 45-53 Gy	42	11	10

¹3-yr overall survival. AC: Adenocarcinoma; NS: Not significant; RT: Radiation therapy; SCC: Squamous cell carcinoma.