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World J Gastrointest Oncol. May 15, 2014; 6(5): 104-111
Published online May 15, 2014. doi: 10.4251/wjgo.v6.i5.104
Published online May 15, 2014. doi: 10.4251/wjgo.v6.i5.104
Table 2 Comparison of randomized trials assessing follow-up after colorectal cancer curative surgery n (%)
| Trial | Cancer stage included | Enrolled (n) | Recurrences | Time to cancer detection (mo) | Metastases surgeries (n) | Overall 5-yr survival | Disease free 5-yr survival | Survival after met surgery |
| Ohlsson 1995 | ||||||||
| Total | Dukes A, B, C | 107 | 35 (33) | |||||
| Intensive | 53 | 17 (32) | 20 (median) | 5 | 75 | 78 | 29% 5 yr | |
| Control | 54 | 18 (33) | 24 (median) | 3 | 67 | 71 | 22% 5 yr | |
| Makela 1995 | ||||||||
| Total | Dukes A, B, C | 106 | 43 (41) | 8 | 58 | Overall 3 pts mean 26 mo survival | ||
| Intensive | 52 | 22 (42) | 10 (mean) | 5 | 59 | |||
| Control | 54 | 21 (39) | 15 (mean) | 3 | 54 | |||
| Pietra 1998 | ||||||||
| Total | Dukes B, C | 207 | 82 (39) | Overall 8 pts mean 29 mo survival | ||||
| Intensive | 104 | 41 (39) | 10.3 (mean) | 21 | 73 | 68 | ||
| Control | 103 | 41 (40) | 20.2 (mean) | 6 | 58 | 53 | ||
| Rodriegez-Moranta 2006 | ||||||||
| Total | TNM II and III | 259 | 69 (26) | NA | ||||
| Intensive | 127 | 35 (27) | 39 (mean) | 18 | 75 | NA | ||
| Control | 132 | 34 (26) | 38 (mean) | 10 | 73 | |||
| Secco 2001 | ||||||||
| Risk adapted intensive | Low risk vs high risk | 108 | 74 (68) | Total | 31 | 48 | NA | NA |
| Risk adapted low intensive | 84 | 27 (32) | 13.5 (mean) | 82 | ||||
| Minimal follow-up: High risk | 84 | 58 (69) | 13 | 35 | ||||
| Minimal follow-up: Low risk | 61 | 25 (40) | 60 |
- Citation: Augestad KM, Rose J, Crawshaw B, Cooper G, Delaney C. Do the benefits outweigh the side effects of colorectal cancer surveillance? A systematic review. World J Gastrointest Oncol 2014; 6(5): 104-111
- URL: https://www.wjgnet.com/1948-5204/full/v6/i5/104.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v6.i5.104