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World J Gastrointest Oncol. Mar 15, 2014; 6(3): 55-66
Published online Mar 15, 2014. doi: 10.4251/wjgo.v6.i3.55
Published online Mar 15, 2014. doi: 10.4251/wjgo.v6.i3.55
Figure 4 Lipid peroxidation and mutagens.
Lipids containing PUFA (LH) are oxidized to form damaging lipid peroxy radicals (LOO.). These radicals can generate mutagenic aldehydes such as malondialdehyde (MDA) and 4-hydroxy-2-nonenal (4-HNE) from n-6 PUFAs. Lipid peroxidation can be initiated by the formation of highly reactive hydroxyl radicals (.OH) arising from the Fenton reaction.
- Citation: Stone WL, Krishnan K, Campbell SE, Palau VE. The role of antioxidants and pro-oxidants in colon cancer. World J Gastrointest Oncol 2014; 6(3): 55-66
- URL: https://www.wjgnet.com/1948-5204/full/v6/i3/55.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v6.i3.55