Prognostic factors in resectable cholangiocarcinoma patients: Carcinoembryonic antigen, lymph node, surgical margin and chemotherapy

Table 3 Differences of survival time among significant variable factors when analyzed by univariate analysis

Variable	Median survival (mo)	95%CI	P value
Albumin (g/dL)			0.04
< 3	12.8	7.1-18.4
≥ 3	19.1	14.6-23.5
CEA (ng/mL)			0.02
< 2.5	27.7	14.1-41.3
≥ 2.5	16.5	13.0-20.0
AJCC staging			< 0.001
0	Not reached
1	Not reached
2	23.5	16.9-30.1
3	12.8	10.6-15.1
4	12.5	9.3-15.7
Tumor grading			0.01
Well differentiated	17.9	12.6-23.2
Moderate differentiated	7.7	0.0-21.7
Margin in resection group			0.001
Negative	26.7	19.6-33.8
Positive	14.1	11.9-16.4
pT stage			< 0.001
0	Not reached
1	28.6	23.1-34.1
2	19.9	12.9-26.9
3	12.8	9.4-16.3
4	15.5	9.9-21.1
pN stage			< 0.001
0	25.1	20.0-30.1
1	10.0	6.7-13.3
Receiving adjuvant chemotherapy			0.01
Yes	21.6	16.9-26.4
No	13.4	10.7-16.2

CEA: Carcinoembryonic antigen; AJCC: American Joint Committee on Cancer. pN: Pathologic node; pT: Pathologic tumor.