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©2012 Baishideng.
World J Gastrointest Oncol. Jun 15, 2012; 4(6): 138-144
Published online Jun 15, 2012. doi: 10.4251/wjgo.v4.i6.138
Published online Jun 15, 2012. doi: 10.4251/wjgo.v4.i6.138
Alcohol-dependent siblings | Non-alcoholic siblings | |
Global methylation index for 1287 CpG sites | ||
Mean methylation (SD) | 0.282 (0.016) | 0.282 (0.012) |
Median methylation (SD) | 0.082 (0.010) | 0.079 (0.009) |
Range | 0.01-0.97 | 0.01-0.97 |
Sib pair difference in global methylation level at each of 1287 sites (alcoholic minus non-alcoholic sibling methylation level) | ||
Mean difference (SD) | 0.00005 (0.019) | |
Replicate pair difference in methylation level at each of 1287 sites (3 non-alcoholic and alcoholic siblings with replicate bisulfite treatment and methylation quantification) | ||
Mean difference (SD) | 0.0008 (0.006) | 0.001 (0.003) |
- Citation: Thapar M, Covault J, Hesselbrock V, Bonkovsky HL. DNA methylation patterns in alcoholics and family controls. World J Gastrointest Oncol 2012; 4(6): 138-144
- URL: https://www.wjgnet.com/1948-5204/full/v4/i6/138.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v4.i6.138