Tumors of ampulla of Vater: A case series and review of chemotherapy options

doi:10.4251/wjgo.v4.i3.60

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Mar 15, 2012 (publication date) through Nov 28, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Mar 15, 2012; 4(3): 60-67
Published online Mar 15, 2012. doi: 10.4251/wjgo.v4.i3.60

Table 3 Studies on adjuvant chemo-radiotherapy

	n	Study design	Treatment group	Control group	Treatment benefit	Author
Pancreatic + periampullary	207	RCT (EORTC)	CCRT	Observation	No	Klinkenbijl et al[36] 1999
Ampullary	104	Retrospective	CCRT	Observation	No	Sikora et al[37] 2005
Ampullary	125	Retrospective	CCRT	Observation	Yes (node+)	Bhatia et al[38] 2006
Pancreatic + periampullary	218	RCT	CCRT	Observation	No	Smeenk et al[39] 2007
Ampullary	96	Retrospective	CCRT	Observation	No	Krishnan et al[40] 2008
Pancreatic + periampullary	120	RCT	CAI + RT	Observation	Yes	Morak et al[41] 2008
Ampullary	118	Retrospective	CCRT	Observation	Yes	Kim et al[42] 2009
Ampullary	111	Retrospective	CCRT	Observation	No	Zhou et al[43] 2009
Extra hepatic biliary cancer	120	Retrospective	CCRT + CT	CCRT	Yes	Lim et al[44] 2009
Ampullary	186	Retrospective	CCRT	Observation	Yes	Narang et al[45] 2011

RCT: Randomized controlled trial; CCRT: Combined chemio-radiotherapy; CAI: Celiac axis infusion (intra-arterial chemotherapy); RT: Radiotherapy; CT: Chemotherapy.

Citation: Romiti A, Barucca V, Zullo A, Sarcina I, Di Rocco R, D’Antonio C, Latorre M, Marchetti P. Tumors of ampulla of Vater: A case series and review of chemotherapy options. World J Gastrointest Oncol 2012; 4(3): 60-67
URL: https://www.wjgnet.com/1948-5204/full/v4/i3/60.htm
DOI: https://dx.doi.org/10.4251/wjgo.v4.i3.60