Lymph node ratio and preoperative CA 19-9 levels predict overall survival and recurrence-free survival in patients with resected pancreatic adenocarcinoma

Table 5 Hazard ratios of variables analyzed on multivariable analysis for overall survival and recurrence-free survival

	Overall survival			Recurrence-free survival
	HR	95% CI	P value	HR	95% CI	P value
Lymph node ratio (0.29 vs 0)	1.66	1.226-2.225	< 0.001	1.50	1.109-2.028	0.008
Preoperative CA 19-9 (378.25 vs 47.5)	1.27	1.001-1.619	0.049	1.24	0.97-1.584	0.086
Tumor grade (I vs II-III)	0.91	0.539-1.532	0.720	1.38	0.813-2.344	0.232
Perineural invasion (Neg vs Pos)	0.54	0.256-1.145	0.108	0.45	0.204-1.002	0.050
Adjuvant chemotherapy (no vs yes)	1.48	0.876-2.505	0.142	1.32	0.744-2.357	0.339

HR: Hazards ratio; CA: Carbohydrate antigen; Neg: Negative; Pos: Positive.