Molecular predictors of gemcitabine response in pancreatic cancer

doi:10.4251/wjgo.v3.i11.153

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Nov 15, 2011 (publication date) through Nov 4, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Nov 15, 2011; 3(11): 153-164
Published online Nov 15, 2011. doi: 10.4251/wjgo.v3.i11.153

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Figure 3 Simplified representation of the web that regulates epithelial to mesenchymal transition or the reverse process mesenchymal to epithelial transition. Epithelial to mesenchymal transition (EMT) promotion is associated with gemcitabine resistance. Arrows denote up-regulation or activation and т type joinings denote down-regulation or inhibition. MET: Mesenchymal to epithelial transition; ZEB: Zinc finger E-box binding; TGFβ: Transforming growth factor β; NF-κB: Nuclear factor-κB.

Citation: Voutsadakis IA. Molecular predictors of gemcitabine response in pancreatic cancer. World J Gastrointest Oncol 2011; 3(11): 153-164
URL: https://www.wjgnet.com/1948-5204/full/v3/i11/153.htm
DOI: https://dx.doi.org/10.4251/wjgo.v3.i11.153