Aberrant promoter methylation of p16 in colorectal adenocarcinoma in North Indian patients

doi:10.4251/wjgo.v2.i7.295

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jul 15, 2010; 2(7): 295-303
Published online Jul 15, 2010. doi: 10.4251/wjgo.v2.i7.295

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Figure 1 Methylation specific polymerase chain reaction for p16 gene in colorectal tumor tissue, adjoining and normal mucosa. U: Polymerase chain reaction (PCR) with primers for unmethylated p16; M: PCR with primers for methylated p16; MW: Molecular weight marker; - ve: negative control (without template); + ve: Normal lymphocyte DNA completely methylated with CpG methylase (M.sss1) used as a positive control for methylation; N: Normal mucosa; A: Adjoining mucosa; T: tumor tissue.

Citation: Malhotra P, Kochhar R, Vaiphei K, Wig JD, Mahmood S. Aberrant promoter methylation of p16 in colorectal adenocarcinoma in North Indian patients. World J Gastrointest Oncol 2010; 2(7): 295-303
URL: https://www.wjgnet.com/1948-5204/full/v2/i7/295.htm
DOI: https://dx.doi.org/10.4251/wjgo.v2.i7.295