Experience with peritoneal mesothelioma at the Milan National Cancer Institute

Figure 3 Effects of siRNA-mediated survivin down-regulation on the apoptotic response of STO cells to cisplatin and doxorubicin. The percentage of cells with an apoptotic morphology with respect to the overall population as assessed by fluorescence microscopy in STO cells exposed to oligofectamine alone (empty column) and transfected with control siRNA (gray column) or survivin siRNA (black column) in the absence or presence of different cisplatin or doxorubicin concentrations. Data represent mean ± SD of 3 independent experiments. ^aP < 0.05; ^bP < 0.01; ^dP < 0.001; Student’s t test.