Early-onset gastric cancer: Learning lessons from the young

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Feb 15, 2010 (publication date) through Nov 27, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2010; 2(2): 59-64
Published online Feb 15, 2010. doi: 10.4251/wjgo.v2.i2.59

Table 1 Environmental and other risk factors for conventional gastric cancer

Increased risk of gastric cancer	Decreased risk of gastric cancer
CHD1, TP53, BRCA2 germline mutation	Fruit and vegetables
Hereditary non-polyposis colorectal cancer	Ascorbic acid
Helicobacter pyloriinfection	Carotenoids
Ebstein barrvirus infection	Folates
Cigarette smoking	Tocopherols
Smoked or cured meat and fish	Cereal fibres
Pickled vegetables	Numerous polymorphisms (as mentioned under increased risk)
Chilli peppers
Alcohol
Exposure to nitrosamines + inorganic dust
Obesity
Pharmacological gastric acid suppression
IL-1β-31 polymorphism
1195 COX-2 polymorphism
Other polymorphisms: MTHFR, PSCA, XPA, XPC, ERCC2, GSTT1, SULT1A1, NAT2, EPHX1, Toll-like receptor 4

Citation: Milne AN, Offerhaus GJA. Early-onset gastric cancer: Learning lessons from the young. World J Gastrointest Oncol 2010; 2(2): 59-64
URL: https://www.wjgnet.com/1948-5204/full/v2/i2/59.htm
DOI: https://dx.doi.org/10.4251/wjgo.v2.i2.59