Cancer and age related colonic crypt deficiencies in cytochrome c oxidase I

Table 1 Tumor marginal cytochrome c oxidase I deficiency, cluster size and tumor cytochrome c oxidase I deficiency

Patient No.	Total No. of crypts at margin of tumor in tissue section	No. of CcOI deficient crypts at margin of tumor	% of crypts at margin of tumor that are CcOI deficient [100 × (CcOI-deficient crypts/total crypts)]	Maximum cluster size (No. of deficient crypts adjacent to each other) of deficient crypts	Approximate % of area in tumor with CcOI deficiency
1	772	765	99	410	40
2	194	189	97	189	3
3	38	37	97	37	80
4	61	58	95	39	2
5	145	137	94	81	30
6	131	115	88	94	N/A1
7	56	45	80	20	5
8	43	31	72	4	2
9	31	22	71	7	2
10	15	10	67	8	1
11	24	16	66	3	15
12	126	82	65	32	4
13	17	9	53	3	28
14	59	20	34	6	10
15	47	16	34	5	7
16	10	3	30	2	1
17	244	68	29	11	50
18	341	92	27	6	1
19	126	34	27	12	10
20	133	33	25	5	18
21	162	35	22	4	10
22	286	63	22	6	N/A
23	72	16	22	4	3
24	892	181	20	8	N/A
25	237	44	19	5	20
26	633	111	18	16	15
27	120	19	16	5	N/A
28	634	97	15	5	8
29	1813	262	14	14	N/A
30	61	7	11	2	2
31	239	26	11	4	35
32	396	40	10	4	N/A
33	79	7	9	1	5
34	80	6	8	3	N/A
35	140	10	7	3	50
Overall average percent			42.1		16.4

¹N/A indicates that no tumor area was available in the tissue section as cut, and only the margin of the tumor was present. CcOI: Cytochromecoxidase I.