Impact of SLC16A8 on tumor microenvironment and angiogenesis in colorectal cancer: New therapeutic target insights

Figure 7 Effect of SLC16A8 on tumor growth. A-C: The impact of SLC16A8 knockdown on tumor growth; D: Effect of SLC16A8 knockdown on Ki67 expression in tumor; E: The effect of SLC16A8 knockdown on expression of HIF-1α and SLC16A8; F: Effect of SLC16A8 knockdown on HIF-1α expression; G: SLC16A8 knockdown promoted apoptosis in tumor; H: H&E staining was used to have a histopathological examination of tumors; I: SLC16A8 knockdown suppressed lactic acid in serum; J and K: SLC16A8 knockdown altered expression of Warburg effect- and endothelial-mesenchymal transition-related proteins’ expression. ^aP < 0.05, ^bP < 0.01, vs NC.