Impact of SLC16A8 on tumor microenvironment and angiogenesis in colorectal cancer: New therapeutic target insights

Figure 6 SLC16A8 siRNA reverses the effects of hypoxia on cell endothelial-mesenchymal transition of HUVECs. A and B: The effect of SLC16A8 siRNA on the proliferation of hypoxia treated cells; C and D: SLC16A8 siRNA can affect the migration (C) and invasion (D) of hypoxic HUVECs; E: SLC16A8 siRNA can affect the expression level of E-cadherin, N-cadherin and Vimentin in hypoxia treated cells; F: Effect of SLC16A8 siRNA on the ability of endothelial cells to form tubes after co culture of colorectal cancer cells with hypoxia. ^aP < 0.05, ^bP < 0.01.