Impact of SLC16A8 on tumor microenvironment and angiogenesis in colorectal cancer: New therapeutic target insights

doi:10.4251/wjgo.v17.i4.99188

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Apr 15, 2025 (publication date) through Mar 28, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Apr 15, 2025; 17(4): 99188
Published online Apr 15, 2025. doi: 10.4251/wjgo.v17.i4.99188

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Figure 3 Effect of hypoxia on endothelial-mesenchymal transition of HUVEC co-cultured with colorectal cancer cells. A and B: Effect of hypoxia on cell viability; C and D: Effect of hypoxia on migration (C) and invasion (D) of HUVECs; E: Effect of hypoxia on the ability of endothelial cells’ tube formation; F: Hypoxia affected the expression of E-cadherin, N-cadherin and Vimentin in HUVECs. ^aP < 0.05, ^bP < 0.01.

Citation: Tian HP, Xiao ZX, Su BW, Li YX, Peng H, Meng CY. Impact of SLC16A8 on tumor microenvironment and angiogenesis in colorectal cancer: New therapeutic target insights. World J Gastrointest Oncol 2025; 17(4): 99188
URL: https://www.wjgnet.com/1948-5204/full/v17/i4/99188.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i4.99188