Oesophageal cancer-specific mortality risk and public health insurance: Prospective cohort study from China

Table 3 Association of insurance type and out-of-pocket rates with risk of cancer specific and all-cause mortality

Variables	Patients (n)	Events (n)	Rate	1Model A		2Model B		3Model C
				HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value
Overall mortality
Insurance type	2543	1438	13.46
URBMI	1871	1012	13.24	1		1		1
UEBMI	672	426	17.43	1.199 (1.066-1.348)	0.002	1.29 (1.145-1.453)	< 0.001	1.233 (1.093-1.391)	0.001
Out-of-pocket ratio
≤ 60%	1450	924	17.50	1		1		1
> 60%	1093	514	10.13	0.85 (0.761-0.95)	0.004	0.715 (0.632-0.809)	< 0.001	0.742 (0.655-0.84)	< 0.001
Cancer-specific mortality
Insurance type	2543	1106	8.64
URBMI	1871	776	8.63	1		1		1
UEBMI	672	330	10.74	1.218 (1.066-1.392)	0.004	1.285 (1.122-1.472)	< 0.001	1.223 (1.066-1.402)	0.004
Out-of-pocket ratio
≤ 60%	1450	741	11.74	1		1		1
> 60%	1093	365	6.01	0.747 (0.657-0.850)	< 0.001	0.649 (0.562-0.748)	< 0.001	0.668 (0.579-0.772)	< 0.001

¹Model A: We adjusted for demographic factors, including age, sex, marriage, nation, body mass index, Karnofsky performance status, base disease, pathological, tumor-node-metastasis.

²Model B: Based on model A, we additionally adjusted for treatment types, including radiotherapy, chemotherapy, surgery, immunotherapy, targeted.

³Model C: Based on model B, we additionally adjusted for blood index, including fibrinogen, β2 micro-globulin, lactate dehydrogenase, platelet-lymphocyte ratio, lymphocyte-monocyte ratio, neutrophil-lymphocyte ratio, albumin/globulin, cluster of differentiation 4/cluster of differentiation 8.

HR: Hazard ratio; CI: Confidence interval; URBMI: Urban and rural resident basic medical insurance; UEBMI: Urban employee basic medical insurance.