Oesophageal cancer-specific mortality risk and public health insurance: Prospective cohort study from China

Table 2 The relationship between treatment style and insurance type and out-of-pocket ratio

Variables	n (%)	1Model A		2Model B		3Model C
		OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
Radiotherapy
Insurance type
URBMI	657 (35.11)	1		1		1
UEBMI	332 (49.4)	1.874 (1.561-2.25)	< 0.001	1.823 (1.509-2.203)	< 0.001	1.949 (1.606-2.365)	< 0.001
Out-of-pocket ratio
≤ 60%	823 (56.76)	1		1		1
> 60%	166 (15.19)	0.124 (0.101-0.152)	< 0.001	0.124 (0.101-0.152)	< 0.001	0.118 (0.096-0.146)	< 0.001
Chemotherapy
Insurance type
URBMI	131 (7.00)	1		1		1
UEBMI	80 (11.90)	1.375 (1.139-1.659)	0.001	1.283 (1.052-1.566)	0.014	1.333 (1.089-1.632)	0.005
Out-of-pocket ratio
≤ 60%	136 (9.38)	1		1		1
> 60%	75 (6.86)	0.351 (0.294-0.418)	< 0.001	0.363 (0.302-0.437)	< 0.001	0.351 (0.291-0.423)	< 0.001
Surgery
Insurance type
URBMI	742 (39.66)	1		1		1
UEBMI	313 (46.58)	0.977 (0.813-1.173)	0.800	1.075 (0.881-1.312)	0.478	1.106 (0.904-1.354)	0.329
Out-of-pocket ratio
≤ 60%	738 (50.9)	1		1		1
> 60%	317 (29)	1.599 (1.36-1.88)	< 0.001	1.351 (1.134-1.609)	0.001	1.344 (1.126-1.603)	0.001
Immunotherapy
Insurance type
URBMI	871 (46.55)	1		1		1
UEBMI	307 (45.68)	1.889 (1.396-2.556)	< 0.001	1.763 (1.292-2.406)	< 0.001	1.755 (1.281-2.403)	< 0.001
Out-of-pocket ratio
≤ 60%	598 (41.24)	1		1		1
> 60%	580 (53.06)	0.683 (0.507-0.92)	0.012	0.729 (0.538-0.989)	0.042	0.699 (0.514-0.951)	0.023
Targeted
Insurance type
URBMI	131 (7)	1		1		1
UEBMI	80 (11.9)	3.702 (2.393-5.727)	< 0.001	3.525 (2.253-5.515)	< 0.001	3.857 (2.443-6.089)	< 0.001
Out-of-pocket ratio
≤ 60%	136 (9.38)	1		1		1
> 60%	75 (6.86)	0.224 (0.127-0.394)	< 0.001	0.229 (0.129-0.407)	< 0.001	0.215 (0.12-0.385)	< 0.001

¹Model A: We adjusted for demographic factors, including age, sex, marriage, nation, body mass index.

²Model B: Based on model A, we also adjusted for clinical characteristics, including Karnofsky performance status, base disease, pathological, tumor-node-metastasis.

³Model C: Based on model B, we additionally adjusted for blood index, including fibrinogen, β2 micro-globulin, lactate dehydrogenase, platelet-lymphocyte ratio, lymphocyte-monocyte ratio, neutrophil-lymphocyte ratio, albumin/globulin, cluster of differentiation 4/cluster of differentiation 8.

OR: Odds ratio; CI: Confidence interval; URBMI: Urban and rural resident basic medical insurance; UEBMI: Urban employee basic medical insurance.