Using bioinformatics methods to elucidate fatty acid-binding protein 4 as a potential biomarker for colon adenocarcinoma

Figure 5 Comparison of immune characteristics associated with fatty acid-binding protein 4 expression. A: The expression level of fatty acid-binding protein 4 (FABP4) was significantly positively correlated with the infiltration level of immune cells in colon adenocarcinoma; B: Comparisons of the stromal score, immune score, ESTIMATE score, and tumor purity between the high FABP4 expression group and the low FABP4 expression group; C: Proportion of immune cells in the high FABP4 expression group and low FABP4 expression group; D: Comparison of immune cell infiltration between the high FABP4 expression group and the low FABP4 expression group. P values are labeled with asterisks. NS: Not significant; ^aP < 0.05; ^bP < 0.01; and ^cP < 0.001; COAD: Colon adenocarcinoma; ESTIMATE: Estimation of STromal and Immune cells in MAlignant Tumor tissues using Expression data; ssGSEA: Single-sample gene set enrichment analysis.