Using bioinformatics methods to elucidate fatty acid-binding protein 4 as a potential biomarker for colon adenocarcinoma

Figure 4 Results of the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes functional enrichment analyses, gene set enrichment analysis and gene set variation analysis. A-C: Analysis of the biological process, cellular component and molecular function terms of genes strongly associated with fatty acid-binding protein 4 (FABP4); D: Kyoto Encyclopedia of Genes and Genomes analysis of genes strongly associated with FABP4; E: GSEA of genes highly correlated with FABP4; F: Correlation analysis between FABP4 expression and functional enrichment scores. The heatmap shows the expression of FABP4 and the enrichment scores of the functions of the genes in each patient in The Cancer Genome Atlas database. The samples were arranged in ascending order of FABP4 expression. TCGA: The Cancer Genome Atlas; KEGG: Kyoto Encyclopedia of Genes and Genomes; FABP4: Fatty acid-binding protein 4; CC: Cellular component; BP: Biological process; MF: Molecular function.