Identification of key hub genes associated with anti-gastric cancer effects of lotus plumule based on machine learning algorithms

doi:10.4251/wjgo.v17.i4.103048

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Apr 15, 2025 (publication date) through Mar 28, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Apr 15, 2025; 17(4): 103048
Published online Apr 15, 2025. doi: 10.4251/wjgo.v17.i4.103048

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Figure 8 Relationship between hub genes and immune infiltration. A: Scatter plot of correlation of StromalScore, ImmuneScore, and ESTIMATEScore with hub genes; B: Heatmap of correlation between hub genes and immune checkpoints. Blue color represents negative correlation and red color represents positive correlation; C: Single-cell sequencing and single-cell annotation map of hub genes. Different colors represent different sets of cells. CA9: Carbonic anhydrase 9; FBP1: Fructose-bisphosphatase 1; PRMT1: Protein arginine methyltransferase 1; AKR1B10: Aldo-keto reductase family 1 member B10.

Citation: Meng FD, Jia SM, Ma YB, Du YH, Liu WJ, Yang Y, Yuan L, Nan Y. Identification of key hub genes associated with anti-gastric cancer effects of lotus plumule based on machine learning algorithms. World J Gastrointest Oncol 2025; 17(4): 103048
URL: https://www.wjgnet.com/1948-5204/full/v17/i4/103048.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i4.103048