Investigation of high-mobility group box 1 variants with lymph node status and colorectal cancer risk

Table 1 Distribution of selected risk factors and demographic variables in colorectal cancer cases and controls

Variable	Cases (n = 1003)		Controls (n = 1303)		P value1
	n	%	n	%
Age (years)	61.10 ± 12.17		61.40 ± 9.61		0.496
Age (years)					0.605
< 61	451	44.97	600	46.05
≥ 61	552	55.03	703	53.95
Sex					0.867
Male	620	61.81	801	61.47
Female	383	38.19	502	38.53
Smoking status					0.002a
Never	744	74.18	1038	79.66
Ever	259	25.82	265	20.34
Alcohol use					< 0.001a
Never	829	82.65	1167	89.56
Ever	174	17.35	136	10.44
BMI (kg/m2)
< 24	670	66.80	688	52.80	< 0.001a
≥ 24	333	33.20	615	47.20
Site of tumor
Colon cancer	431	42.97
Rectum cancer	572	57.03

^aP < 0.05.

¹Two-sided χ² test and Student t-test.

BMI: Body mass index.