Significance of monitoring imatinib plasma concentration in second-line treatment decisions for c-kit 11 gene-mutated gastrointestinal stromal tumors

doi:10.4251/wjgo.v17.i3.98746

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Mar 15, 2025 (publication date) through Feb 21, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Mar 15, 2025; 17(3): 98746
Published online Mar 15, 2025. doi: 10.4251/wjgo.v17.i3.98746

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Figure 4 Kaplan-Meier curves of overall survival between the dose-escalation group (Group A) and drug-switch group (Group B). A: The Kaplan-Meier curves indicated that the dose-escalation group (Group A) had a longer overall survival (OS) than the drug-switch group (Group B) (log-rank P = 0.02); B: The Kaplan-Meier curves indicated that there was no significant difference in OS between the dose-escalation group (Group A) and drug-switch group (Group B) (log-rank P = 0.97).

Citation: Li HT, Du YY, Huang Z, Li JJ, Zhang J. Significance of monitoring imatinib plasma concentration in second-line treatment decisions for c-kit 11 gene-mutated gastrointestinal stromal tumors. World J Gastrointest Oncol 2025; 17(3): 98746
URL: https://www.wjgnet.com/1948-5204/full/v17/i3/98746.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i3.98746