Transmembrane protein 176B promotes epithelial-mesenchymal transition in colorectal cancer through inflammasome inhibition

Figure 1 sh-Transmembrane protein 176B inhibits tumor metastasis in colon cancer mice. A: Fluorescence imaging was utilized to observe tumor metastasis in mice, with the total and average distribution of tumor fluorescence intensity being analyzed across different groups in mice; B and C: Colon tumor tissues in mice were harvested and subjected to Hematoxylin and eosin staining with magnifications of 200 × (scale bar 100 μm) and 400 × (scale bar 50 μm). For each group, n = 3. ^aP < 0.05; ^bP < 0.01. sh-TMEM176B: Short hairpin RNA targeting transmembrane protein 176B, sh-NC: shRNA-negative control.