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©The Author(s) 2025.
World J Gastrointest Oncol. Mar 15, 2025; 17(3): 103296
Published online Mar 15, 2025. doi: 10.4251/wjgo.v17.i3.103296
Published online Mar 15, 2025. doi: 10.4251/wjgo.v17.i3.103296
Table 3 Univariate logistic regression analysis of risk factors on low-grade intraepithelial neoplasia progression
Characteristic | Progress | Non-progress | OR (95%CI) | P value |
Age | ||||
≥ 60 | 21 | 92 | 3.114 (1.356-7.153) | 0.007 |
< 60 | 12 | 171 | Ref. | |
Gender | ||||
Male | 13 | 150 | 1.795 (0.785-4.105) | 0.166 |
Female | 20 | 113 | Ref. | |
Multiple location | ||||
Yes | 5 | 5 | 10.838 (2.023-58.076) | 0.005 |
No | 28 | 258 | Ref. | |
Lesion size | ||||
≥ 2 cm | 15 | 40 | 4.189 (1.751-10.018) | 0.001 |
< 2 cm | 18 | 223 | Ref. | |
Congestion | ||||
Yes | 10 | 79 | 1.208 (0.474-3.078) | 0.157 |
No | 23 | 187 | Ref. | |
Form | ||||
Protuberant | 11 | 107 | 0.757 (0.413-1.387) | 0.367 |
Flat | 18 | 117 | 0.966 (0.587-2.236) | 0.438 |
Central depression | 4 | 39 | Ref. | |
Ulceration | ||||
Yes | 16 | 74 | 2.685 (1.161-6.207) | 0.021 |
No | 17 | 189 | Ref. | |
Atrophy | ||||
Yes | 18 | 125 | 1.107 (0.482-2.542) | 0.811 |
No | 15 | 1381 | Ref. | |
Intestinal metaplasia | ||||
Yes | 159 | 104 | 0.815 (0.346-1.922) | 0.640 |
No | 20 | 13 | Ref. | |
H. pylori infection | ||||
Yes | 29 | 163 | 4.448 (1.159-13.027) | 0.006 |
No | 4 | 100 | Ref. |
- Citation: Liu YL, Liu J, Wang YT. Risk of progression to high-grade intraepithelial neoplasia and gastric cancer: A multi-center prospective study in Anhui Province, China. World J Gastrointest Oncol 2025; 17(3): 103296
- URL: https://www.wjgnet.com/1948-5204/full/v17/i3/103296.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v17.i3.103296