Expression significance of biomarker MORC4 in colorectal cancer patients and its relationship with pathological features and prognosis

Table 3 Comparison of high MORC family CW-type zinc finger 4 expression rate in colorectal cancer tissue among patients with different pathological characteristics, n (%)

Pathological characteristics	Cases (n = 143)	High MORC4 expression (n = 89)	χ²	P value
Gender	-	-	0.705	0.401
Male	81	48 (59.26)	-	-
Female	62	41 (66.13)	-	-
Age (years)	-	-	0.356	0.550
< 60	19	13 (68.42)	-	-
≥ 60	124	76 (61.29)	-	-
Tumor location	-	-	0.015	0.902
Left side	112	70 (62.50)	-	-
Right side	31	19 (61.29)	-	-
Tumor diameter (cm)	-	-	0.827	0.362
≤ 5	94	56 (59.57)	-	-
> 5	49	33 (67.35)	-	-
Degree of differentiation	-	-	5.772	0.016
Low differentiation	21	18 (85.71)	-	-
Moderate + high differentiation	122	71 (58.20)	-	-
T stage	-	-	0.911	0.339
T1 + T2 stage	13	6 (46.15)	-	-
T3 + T4 stage	130	83 (63.85)	-	-
N stage	-	-	5.760	0.016
N0 stage	88	48 (54.55)	-	-
Nx stage	55	41 (74.55)	-	-
M stage	-	-	7.612	0.005
M0 stage	127	74 (58.27)	-	-
M1 stage	16	15 (93.75)	-	-
TNM stage	-	-	7.706	0.005
I + II	85	45 (52.94)	-	-
III + IV	58	44 (75.86)	-	-
Serum CEA (μg/L)	-	-	19.270	< 0.001
< 5	67	29 (43.28)	-	-
≥ 5	76	60 (78.95)	-	-

MORC4: MORC family CW-type zinc finger 4; TNM: Tumor-nodes-metastasis; CEA: Carcinoembryonic antigen.