To investigate the effect and mechanism of tetrahydrocurcumin on hepatocellular carcinoma based on phosphoinositide 3-kinases/AKT signaling pathway

doi:10.4251/wjgo.v17.i3.102187

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Mar 15, 2025; 17(3): 102187
Published online Mar 15, 2025. doi: 10.4251/wjgo.v17.i3.102187

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Figure 13 Schematic diagram of the phosphoinositide 3-kinases/AKT signaling pathway and its downstream multiple effector molecules. RTK: Receptor tyrosine kinases; GPCR: G protein coupled receptor; PIP2: Phosphatidylinositol bisphosphate; PIP3: Phosphatidylinositol trisphosphate; PDK1: Pyruvate dehydrogenase kinase 1; MDM2: Murine double minute 2; Bax: B cell leukemia/lymphoma 2 associated X; Bcl-2: B cell leukemia/lymphoma 2.

Citation: Bao ZC, Liu ZD, Zhang Y, Dai HJ, Jia H, Ren F, Li N, Zhao L, Wang YW, Lv SY, Zhang Y. To investigate the effect and mechanism of tetrahydrocurcumin on hepatocellular carcinoma based on phosphoinositide 3-kinases/AKT signaling pathway. World J Gastrointest Oncol 2025; 17(3): 102187
URL: https://www.wjgnet.com/1948-5204/full/v17/i3/102187.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i3.102187