Irreversible electroporation combined with anti-programmed cell death protein 1 therapy promotes tumor antigen-specific CD8+ T cell response

Figure 1 Establishment of pancreatic cancer model and ablation parameters. A: Schematic drawing of the study design. C57BL/6 mice were enrolled for treatment once the tumor size reached about 10 mm; B: Tumor growth on day 20; C: Irreversible electroporation procedure was performed with two electrodes; D: Ablation parameters (1200 kV/cm, 70 pulses, 70 μs). IRE: Irreversible electroporation; PD-1: Programmed cell death protein 1.