Assessment of new pathological markers in early stage colon cancer: Insights and limitations

Table 2 Relationship of data with risk groups, n (%)

Characterization	Low risk group (n = 25)	High risk group (n = 130)	P value
Age (years)			0.83
< 67	13 (52)	64 (49.2)
≥ 67	12 (48)	66 (50.8)
Gender			0.66
Female	12 (48)	55 (42.3)
Male	13 (52)	75 (56.7)
Tumor location			0.12
Right colon	13 (52)	45 (34.6)
Left colon	12 (48)	85 (65.4)
Pathology			0.17
Mucinous	8 (32)	24 (18.5)
Nonmucinous	17 (68)	106 (81.5)
TIL presence			0.82
Positive	7 (28)	43 (33.1)
Negative	18 (72)	87 (66.9)
PDC			0.51
Positive	13 (52)	78 (60)
Negative	12 (48)	52 (40)
PDC grade (n = 91)			0.99
Grade 1	6 (46.1)	37 (47.4)
Grade 2	3 (23.1)	24 (30.8)
Grade 3	4 (30.8)	17 (21.8)
Tumor budding			0.37
Positive	7 (28)	51 (39.2)
Negative	18 (72)	79 (60.8)
Crohn-like reaction			0.99
Positive	3 (12)	18 (13.8)
Negative	22 (88)	112 (86.2)
Desmoid reaction			0.83
Positive	13 (52)	73 (56.2)
Negative	12 (48)	57 (43.8)
Tumor-stroma ratio			0.80
Low	5 (20)	31 (23.8)
High	20 (80)	99 (76.2)

PDC: Poorly differentiated clusters; TIL: Tumor infiltrating lymphocytes.