Tetrahydrocurcumin-induced apoptosis of hepatocellular carcinoma cells involves the TP53 signaling pathway, as determined by network pharmacology

Figure 9 Tetrahydrocurcumin promoted the apoptosis of HepG2 and Huh7 cells. A: Hoechst 33342 staining was used to detect the apoptosis of HepG2 and Huh7 cells treated with tetrahydrocurcumin (25, 50, or 100 μmol/L) for 48 hours, after photographing under a fluorescence microscope (20 µm); B: Graphs of apoptosis rates of HepG2 and Huh7 cells determined using Hoechst 33342 staining. All data are presented as mean ± SD, n = 3. Compared to the control group, ^aP < 0.05; ^bP < 0.01; THC: Tetrahydrocurcumin.