Identifying adipocyte-derived exosomal miRNAs as potential novel prognostic markers for radiotherapy of esophageal squamous cell carcinoma

Figure 1 Adipocytes enhance the resistance of esophageal cancer cells to radiation therapy. A: Representative images of colony formation and corresponding survival curves for KYSE30 cells; B: Representative images of colony formation and corresponding survival curves for TE-1 cells; C: Flow cytometry analysis of apoptosis in KYSE30 cells; D: Flow cytometry analysis of apoptosis in TE-1 cells. Live cells are located in the lower left quadrant, early apoptotic cells in the lower right quadrant, and late apoptotic cells in the upper right quadrant. The total number of apoptotic cells includes both early and late apoptotic cells, and the apoptosis rates of KYSE30 and TE-1 cells were evaluated. Mean values from three independent experiments are presented and analyzed using the t-test. ^aP < 0.01; ^bP < 0.001.