Colony-stimulating factor 3 and its receptor promote leukocyte immunoglobulin-like receptor B2 expression and ligands in gastric cancer

doi:10.4251/wjgo.v17.i2.97858

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2025; 17(2): 97858
Published online Feb 15, 2025. doi: 10.4251/wjgo.v17.i2.97858

Table 2 Correlation between the protein expression levels of leukocyte immunoglobulin-like receptor B2, angiopoietin-like protein 2, and human leukocyte antigen-G, and colony-stimulating factor 3 receptor in gastric cancer tissues by immunohistochemistry, n (%)

		CSF3R
		High	Low
LILRB2	High	29 (85.3)	0 (0.0)
LILRB2	Low	5 (14.7)	12 (100.0)^a
ANGPTL2	High	21 (61.8)	5 (41.7)
ANGPTL2	Low	13 (38.2)	7 (58.3)
HLA-G	High	29 (85.3)	5 (41.7)
HLA-G	Low^a	5 (14.7)	7 (58.3)^b

^aP < 0.001.

^bP = 0.01.

LILRB2: Leukocyte immunoglobulin-like receptor B2; ANGPTL2: Angiopoietin-like protein 2; HLA-G: Human leukocyte antigen-G; CSF3R: Colony-stimulating factor 3 receptor.

Citation: Wang L, Wu Q, Zhang ZW, Zhang H, Jin H, Zhou XL, Liu JY, Li D, Liu Y, Fan ZS. Colony-stimulating factor 3 and its receptor promote leukocyte immunoglobulin-like receptor B2 expression and ligands in gastric cancer. World J Gastrointest Oncol 2025; 17(2): 97858
URL: https://www.wjgnet.com/1948-5204/full/v17/i2/97858.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i2.97858