LncRNA PCAT6 promotes progression and metastasis of colonic neuroendocrine carcinoma via MAPK pathway

doi:10.4251/wjgo.v17.i2.96230

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Feb 15, 2025 (publication date) through Feb 21, 2025

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2025; 17(2): 96230
Published online Feb 15, 2025. doi: 10.4251/wjgo.v17.i2.96230

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Figure 1 Prostate cancer associated transcript 6 is highly expressed in neuroendocrine carcinomas tissues and cells. A: Immunohistochemistry staining results of CgA in tumor and adjacent nontumor samples collected from patients with neuroendocrine carcinomas (NEC); B: The prostate cancer associated transcript 6 (PCAT6) level in NEC tumor and adjacent nontumor samples was measured by real-time quantitative polymerase chain reaction (RT-qPCR); C: The correlation between CgA and PCAT6 levels in NEC tumor samples was determined via Pearson analysis; D: The PCAT6 level in SW480, LoVo and LCC-18 cells was assessed by RT-qPCR. ^aP < 0.001. NEC: Neuroendocrine carcinomas; PCAT6: Prostate cancer associated transcript 6.

Citation: Wang F, Mu HF, Wang C, Tang Y, Si MY, Peng J. LncRNA PCAT6 promotes progression and metastasis of colonic neuroendocrine carcinoma via MAPK pathway. World J Gastrointest Oncol 2025; 17(2): 96230
URL: https://www.wjgnet.com/1948-5204/full/v17/i2/96230.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i2.96230