Unveiling expression patterns, mechanisms, and therapeutic opportunities of transmembrane protein 106C: From pan-cancers to hepatocellular carcinoma

Figure 6 Biological functions of transmembrane protein 106C in hepatocellular carcinoma cells. A and B: Transmembrane protein 106C (TMEM106C) knockout arrested the cell cycle process during the DNA synthesis phase; C and D: TMEM106C knockout increased both early and late apoptotic rates of hepatocellular carcinoma cells. FL2-A: The area under the curve of the fluorescence signal detected in the FL2 channel; KO: Knockout; PI-A: The area under the curve of the fluorescence signal detected by the flow cytometer after propidium iodide staining; SSC-A: The area under the curve of the side scatter signal; TMEM106C: Transmembrane protein 106C.