BIBR1532 inhibits proliferation and metastasis of esophageal squamous cancer cells by inducing telomere dysregulation

doi:10.4251/wjgo.v17.i1.99376

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Jan 15, 2025 (publication date) through Apr 18, 2025

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World Journal of Gastrointestinal Oncology

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jan 15, 2025; 17(1): 99376
Published online Jan 15, 2025. doi: 10.4251/wjgo.v17.i1.99376

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Figure 5 Proliferation and migration of KYSE150 cells after treatment with BIBR1532 combined with human telomerase reverse transcriptase overexpression. A: Plate colony formation by KYSE150 cells after treatment with BIBR1532 (50 μM) and/or human telomerase reverse transcriptase (hTERT) overexpression for 48 hours; B: Migration evaluated by transwell assay of KYSE150 cells after treatment with BIBR1532 (50 μM) and/or hTERT overexpression for 48 hours; C: Migration evaluated by the scratch assay of KYSE150 cells after treatment with BIBR1532 (50 μM) and/or hTERT overexpression for 48 hours. hTERT: Human telomerase reverse transcriptase.

Citation: Wang Q, Li QR, Xu L, Yuan ZC, Liu X, Tang MJ, Luo M, Zhong XW, Ma Q, Guo XL. BIBR1532 inhibits proliferation and metastasis of esophageal squamous cancer cells by inducing telomere dysregulation. World J Gastrointest Oncol 2025; 17(1): 99376
URL: https://www.wjgnet.com/1948-5204/full/v17/i1/99376.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i1.99376