BIBR1532 inhibits proliferation and metastasis of esophageal squamous cancer cells by inducing telomere dysregulation

Figure 2 Effect of BIBR1532 on the proliferation of KYSE150 and KYSE410 cells. A: Human telomerase reverse transcriptase expression in KYSE150 and KYSE410 cells after exposure to a series of BIBR1532 concentrations; B: Viability of KYSE150 and KYSE410 cells after treatment with various concentrations of BIBR1532 at the indicated time points; C: Plate colony formation by KYSE150 and KYSE410 cells after treatment with various concentrations of BIBR1532 at the indicated time points. ^aP < 0.05 was compared with the control group respectively. P < 0.05 was considered statistically significant. hTERT: Human telomerase reverse transcriptase.