Coagulation indices and fibrinogen degradation products as predictive biomarkers for tumor-node-metastasis staging and metastasis in gastric cancer

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Jan 15, 2025 (publication date) through Dec 23, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jan 15, 2025; 17(1): 98725
Published online Jan 15, 2025. doi: 10.4251/wjgo.v17.i1.98725

Table 1 Comparison of baseline data of patients with gastric cancer, n (%)

Group		Metastases (n = 57)	Absence of metastases (n = 91)	t/χ²	P value
Age (years), mean ± SD		48.61 ± 12.99	48.39 ± 12.16	0.110	0.912
Sex	Male	30 (52.63)	44 (48.35)	0.287	0.591
Sex	Female	27 (47.37)	47 (51.65)	0.287	0.591
BMI (kg/m²), mean ± SD		22.61 ± 2.13	22.42 ± 2.25	0.236	0.814
A family history of malignancy		3 (5.26)	5 (5.49)	0.004	0.952
Present with hypertension		7 (12.28)	12 (13.19)	0.026	0.873
Hyperglycemia		4 (7.02)	10 (10.99)	0.641	0.423
Hyperlipidemia		5 (8.77)	8 (8.79)	< 0.001	0.997
History of alcohol use		12 (19.30)	16 (17.58)	0.273	0.601
Endoscopic tumor site	Cardia (of stomach)	8 (14.04)	17 (18.68)	4.830	0.395
	Fundus of stomach	7 (12.28)	10 (10.99)
	Body of stomach	12 (21.05)	16 (17.58)
	Antrum of stomach	26 (45.61)	47 (51.65)
	Pylorus	2 (3.51)	1 (1.10)
	Whole stomach	2 (3.51)	0 (0.00)
¹⁴C-urea breath test	Masculine	48 (84.21)	72 (79.12)	0.592	0.442
¹⁴C-urea breath test	Feminine character	9 (15.79)	19 (20.88)	0.592	0.442

BMI: Body mass index.

Citation: Shen YQ, Wei QW, Tian YR, Ling YZ, Zhang M. Coagulation indices and fibrinogen degradation products as predictive biomarkers for tumor-node-metastasis staging and metastasis in gastric cancer. World J Gastrointest Oncol 2025; 17(1): 98725
URL: https://www.wjgnet.com/1948-5204/full/v17/i1/98725.htm
DOI: https://dx.doi.org/10.4251/wjgo.v17.i1.98725