Pretreatment red blood cell distribution width as a predictive marker for postoperative complications after laparoscopic pancreatoduodenectomy

Table 2 Surgical details and short-term outcomes of patients who underwent laparoscopic pancreatoduodenectomy, n (%)

Variables	Total (n = 804)	Red blood cell distribution		P value
		< 15.4 (n = 573)	≥ 15.4 (n = 231)
Operative time, minute, mean ± SD	329.14 ± 91.77	325.39 ± 92.03	338.44 ± 90.65	0.068
Blood loss, mL, mean ± SD	156.20 ± 155.38	155.13 ± 160.75	158.85 ± 141.47	0.759
Blood transfusion				< 0.001
No	576 (71.6)	454 (79.2)	122 (52.8)
Yes	228 (28.4)	119 (20.8)	109 (47.2)
Postoperative morbidity				< 0.001
No	421 (52.4)	327 (57.1)	94 (40.7)
Yes	383 (47.6)	246 (42.9)	137 (59.3)
Any POPF	213 (26.5)	132 (23.0)	81 (35.1)	< 0.001
POPF, grade B/C	83 (10.3)	44 (7.7)	39 (16.9)	< 0.001
BL	119 (14.8)	70 (12.2)	49 (21.2)	0.001
BL, grade B/C	89 (11.1)	40 (7.0)	49 (21.2)	< 0.001
DGE	185 (23.0)	126 (22.0)	59 (25.5)	0.279
DGE, grade B/C	62 (7.7)	43 (7.5)	19 (8.2)	0.729
Hemorrhage	113 (14.1)	69 (12.0)	44 (19.0)	0.010
Hemorrhage, B/C	82 (10.2)	47 (8.2)	35 (15.2)	0.003
Intra-abdominal infection	140 (17.4)	90 (15.7)	50 (21.6)	0.045
Clavien-Dino classification				< 0.001
0	421 (52.4)	327 (57.1)	94 (40.7)
I	53 (6.6)	38 (6.6)	15 (6.5)
II	164 (20.4)	102 (17.8)	62 (26.8)
IIIa	117 (14.6)	80 (14.0)	37 (16.0)
IIIb	12 (1.5)	8 (1.4)	4 (1.7)
IVa	16 (2.0)	11 (1.9)	5 (2.2)
IVb	7 (0.9)	3 (0.5)	4 (1.7)
V	14 (1.7)	4 (0.7)	10 (4.3)
CCI score, mean ± SD	20.0 ± 25.5	17.2 ± 23.5	26.9 ± 28.9	< 0.001
< 26.2	519 (64.6)	396 (69.1)	123 (53.2)	< 0.001
≥ 26.2	285 (35.4)	177 (30.9)	108 (46.8)
Hospital stay, day, mean ± SD	13.65 ± 11.98	13.13 ± 10.44	14.93 ± 15.09	0.027

POPF: Postoperative pancreatic fistula; BL: Bile leakage; DGE: Delayed gastric emptying; CCI: Comprehensive complication index.