Interleukin-17A facilitates tumor progression via upregulating programmed death ligand-1 expression in hepatocellular carcinoma

Figure 1 Interleukin-17A regulated programmed cell death ligand-1 expression at the RNA and protein levels in a dose-dependent manner. A: Programmed cell death ligand-1 (PD-L1) mRNA levels were detected by reverse transcription PCR in hepatocellular carcinoma (HCC) cells after treatment with different concentrations of interleukin-17A (IL-17A) for 24 h; B: PD-L1 protein levels were determined by western blotting in HCC cells after treatment with different concentrations of IL-17A for 24 h; C: PD-L1 protein levels in HCC cells were tested by flow cytometry after treatment with 100 ng/mL IL-17A for 24 h. ^aP < 0.05; ^bP < 0.01. PE: Phycoerythrin.