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©The Author(s) 2025.
World J Gastrointest Oncol. Jan 15, 2025; 17(1): 96822
Published online Jan 15, 2025. doi: 10.4251/wjgo.v17.i1.96822
Published online Jan 15, 2025. doi: 10.4251/wjgo.v17.i1.96822
Table 4 Prevalence of DPYD polymorphisms in European populations
| Polymorphism | Photo DPYD Spain[17], n = 8054 | Paulsen Denmark[18], n = 4215 | Pallet France[19], n = 3680 | Henricks Netherland[13], n = 1103 |
| DPYD2A | 55 (0.7) | 43 (1) | 25 (0.67) | 16 (1) |
| DPYD13 | 15 (0.2) | 8 (0.2) | 4 (0.1) | 1 (< 1) |
| Hap3B | 209 (2.6) | 208 (4.9) | 109 (2.96) | 51 (5) |
| c.2846A>T | 105 (1.3) | 57 (1.4) | 34 (0.92) | 17 (2) |
| Total | 384 (4.8) | 316 (7.5) | 172 (4.65) | 85 (8) |
- Citation: D'Amato M, Iengo G, Massa N, Carlomagno C. Dihydropyrimidine dehydrogenase polymorphisms in patients with gastrointestinal malignancies and their impact on fluoropyrimidine tolerability: Experience from a single Italian institution. World J Gastrointest Oncol 2025; 17(1): 96822
- URL: https://www.wjgnet.com/1948-5204/full/v17/i1/96822.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v17.i1.96822