Case Control Study
Copyright ©The Author(s) 2025.
World J Gastrointest Oncol. Jan 15, 2025; 17(1): 96702
Published online Jan 15, 2025. doi: 10.4251/wjgo.v17.i1.96702
Table 3 Analyses of associations between selected genotyped single nucleotide polymorphisms of activin A receptor type 1C on risk of esophageal squamous cell carcinoma
LocusGenotypeControlCaseCo-dominant model
Dominant model
Recessive model
Addictive model
OR (95%CI)
P value
OR (95%CI)/P value
OR (95%CI)/P value
OR (95%CI)/P value
rs4664229TT90883510.3110.894 (0.721-1.107)1.487 (0.624-3.545)0.928 (0.76-1.131)
TC2211770.871 (0.7-1.084)0.2160.3030.370.456
CC9121.45 (0.608-3.459)0.402
rs4556933GG5505871< 0.0010.684 (0.577-0.811)1.349 (1.019-1.786)0.848 (0.743-0.969)
GA4873110.598 (0.498-0.719)< 0.001< 0.0010.0360.015
AA1011181.095 (0.819-1.463)0.541
rs77886248TT106693610.0871.408 (1.019-1.944)0.555 (0.05-6.126)1.366 (0.999-1.870)
TA70881.432 (1.034-1.983)0.0310.0380.6310.051
AA210.569 (0.052-6.29)0.646
rs77263459TT64759310.0870.958 (0.807-1.136)1.169 (0.84-1.628)0.999 (0.870-1.147)
TC4173540.926 (0.773-1.109)0.4050.620.3550.988
CC74771.135 (0.810-1.592)0.462
rs6734630AA90883810.4020.881 (0.711-1.092)1.236 (0.5-3.054)0.906 (0.743-1.105)
GA2211770.868 (0.697-1.08)0.2040.2470.6460.331
GG9101.204 (0.487-2.977)0.688